Epstein-Barr Virus Epitope–Major Histocompatibility Complex Interaction Combined with Convergent Recombination Drives Selection of Diverse T Cell Receptor α and β Repertoires

Recognition modes of individual T cell receptors (TCRs) are well studied, but factors driving the selection of TCR repertoires from primary through persistent human virus infections are less well understood. Using deep sequencing, we demonstrate a high degree of diversity of Epstein-Barr virus (EBV)...

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Detalles Bibliográficos
Autores principales: Gil, Anna, Kamga, Larisa, Chirravuri-Venkata, Ramakanth, Aslan, Nuray, Clark, Fransenio, Ghersi, Dario, Luzuriaga, Katherine, Selin, Liisa K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078470/
https://www.ncbi.nlm.nih.gov/pubmed/32184241
http://dx.doi.org/10.1128/mBio.00250-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078470/
https://www.ncbi.nlm.nih.gov/pubmed/32184241
http://dx.doi.org/10.1128/mBio.00250-20

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