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Epstein-Barr Virus Epitope–Major Histocompatibility Complex Interaction Combined with Convergent Recombination Drives Selection of Diverse T Cell Receptor α and β Repertoires
Recognition modes of individual T cell receptors (TCRs) are well studied, but factors driving the selection of TCR repertoires from primary through persistent human virus infections are less well understood. Using deep sequencing, we demonstrate a high degree of diversity of Epstein-Barr virus (EBV)...
Autores principales: | Gil, Anna, Kamga, Larisa, Chirravuri-Venkata, Ramakanth, Aslan, Nuray, Clark, Fransenio, Ghersi, Dario, Luzuriaga, Katherine, Selin, Liisa K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078470/ https://www.ncbi.nlm.nih.gov/pubmed/32184241 http://dx.doi.org/10.1128/mBio.00250-20 |
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