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Genetic Manipulation of Human Intestinal Enteroids Demonstrates the Necessity of a Functional Fucosyltransferase 2 Gene for Secretor-Dependent Human Norovirus Infection

Human noroviruses (HuNoVs) are the leading cause of nonbacterial gastroenteritis worldwide. Histo-blood group antigen (HBGA) expression is an important susceptibility factor for HuNoV infection based on controlled human infection models and epidemiologic studies that show an association of secretor...

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Detalles Bibliográficos
Autores principales: Haga, Kei, Ettayebi, Khalil, Tenge, Victoria R., Karandikar, Umesh C., Lewis, Miranda A., Lin, Shih-Ching, Neill, Frederick H., Ayyar, B. Vijayalakshmi, Zeng, Xi-Lei, Larson, Göran, Ramani, Sasirekha, Atmar, Robert L., Estes, Mary K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078471/
https://www.ncbi.nlm.nih.gov/pubmed/32184242
http://dx.doi.org/10.1128/mBio.00251-20