Hydrogen Sulfide Mediates Tumor Cell Resistance to Thioredoxin Inhibitor

Thioredoxin (Trx) is a pro-oncogenic molecule that underlies tumor initiation, progression and chemo-resistance. PX-12, a Trx inhibitor, has been used to treat certain tumors. Currently, factors predicting tumor sensitivity to PX-12 are unclear. Given that hydrogen sulfide (H(2)S), a gaseous bio-med...

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Detalles Bibliográficos
Autores principales: Mao, Zhimin, Yang, Xiawen, Mizutani, Sayumi, Huang, Yanru, Zhang, Zhen, Shinmori, Hideyuki, Gao, Kun, Yao, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078679/
https://www.ncbi.nlm.nih.gov/pubmed/32219063
http://dx.doi.org/10.3389/fonc.2020.00252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078679/
https://www.ncbi.nlm.nih.gov/pubmed/32219063
http://dx.doi.org/10.3389/fonc.2020.00252

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