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Hydrogen Sulfide Mediates Tumor Cell Resistance to Thioredoxin Inhibitor
Thioredoxin (Trx) is a pro-oncogenic molecule that underlies tumor initiation, progression and chemo-resistance. PX-12, a Trx inhibitor, has been used to treat certain tumors. Currently, factors predicting tumor sensitivity to PX-12 are unclear. Given that hydrogen sulfide (H(2)S), a gaseous bio-med...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078679/ https://www.ncbi.nlm.nih.gov/pubmed/32219063 http://dx.doi.org/10.3389/fonc.2020.00252 |