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A Novel Indoline Derivative Ameliorates Diabesity-Induced Chronic Kidney Disease by Reducing Metabolic Abnormalities

Both diabetes and obesity (diabesity) contribute significantly to the development of chronic kidney disease (CKD). In search of new remedies to reverse or arrest the progression of CKD, we examined the therapeutic potential of a novel compound, AN1284, in a mouse model of CKD induced by type 2 diabe...

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Detalles Bibliográficos
Autores principales: Permyakova, Anna, Gammal, Asaad, Hinden, Liad, Weitman, Michal, Weinstock, Marta, Tam, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078689/
https://www.ncbi.nlm.nih.gov/pubmed/32218769
http://dx.doi.org/10.3389/fendo.2020.00091