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Development of 2-(4-pyridyl)-benzimidazoles as PKN2 chemical tools to probe cancer
Kinases are signalling proteins which have proven to be successful targets for the treatment of a variety of diseases, predominantly in cancers. However, only a small proportion of kinases (<20%) have been investigated for their therapeutic viability, likely due to the lack of available chemical...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Science Ltd
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078758/ https://www.ncbi.nlm.nih.gov/pubmed/32085971 http://dx.doi.org/10.1016/j.bmcl.2020.127040 |