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Real‐time dissolved carbon dioxide monitoring II: Surface aeration intensification for efficient CO(2) removal in shake flasks and mini‐bioreactors leads to superior growth and recombinant protein yields
Mass transfer is known to play a critical role in bioprocess performance and henceforth monitoring dissolved O(2) (DO) and dissolved CO(2) (dCO(2)) is of paramount importance. At bioreactor level these parameters can be monitored online and can be controlled by sparging air/oxygen or stirrer speed....
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078866/ https://www.ncbi.nlm.nih.gov/pubmed/31840800 http://dx.doi.org/10.1002/bit.27252 |