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The multifaceted Foxp3(fgfp) allele enhances spontaneous and therapeutic immune surveillance of cancer in mice

It is well established that therapeutic impairment of Foxp3(+) Treg in mice and humans favors immune rejection of solid tumors. Less explored is the impact Foxp3 allelic variants may have on tumor incidence, progression and therapy. In this work, we tested and demonstrate that the Foxp3(fgfp) report...

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Detalles Bibliográficos
Autores principales: Almeida‐Santos, José, Bergman, Marie‐Louise, Amendoeira Cabral, Inês, Correia, Vasco, Caramalho, Íris, Demengeot, Jocelyne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078871/
https://www.ncbi.nlm.nih.gov/pubmed/31729760
http://dx.doi.org/10.1002/eji.201948251