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Recombinant FIX Fc fusion protein activity assessment with the one‐stage clotting assay: A multicenter, assessor‐blinded, prospective study in Japan (J‐Field Study)

INTRODUCTION: The one‐stage clotting assay is used to measure factor IX (FIX) activity in patients’ plasma samples and in FIX products for hemophilia treatment. However, the diversity of reagents and instruments has resulted in significant FIX assay variability. METHODS: The accuracy of the one‐stag...

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Detalles Bibliográficos
Autores principales: Fukutake, Katsuyuki, Kobayashi, Tomomi, Sommer, Jurg M., Hirakata, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078902/
https://www.ncbi.nlm.nih.gov/pubmed/31820573
http://dx.doi.org/10.1111/ijlh.13133