Pd‐Catalyzed Asymmetric N‐Allylation of Amino Acid Esters with Exceptional Levels of Catalyst Control: Stereo‐Divergent Synthesis of ProM‐15 and Related Bicyclic Dipeptide Mimetics

A general and powerful method for the stereo‐controlled Pd‐catalyzed N‐allylation of amino acid esters is reported, as a previously largely unsolved synthetic challenge. Employing a new class of tartaric acid‐derived C (2)‐symmetric chiral diphosphane ligands the developed asymmetric amination proto...

Descripción completa

Detalles Bibliográficos
Autores principales: Dohmen, Stephan, Reiher, Martin, Albat, Dominik, Akyol, Sema, Barone, Matthias, Neudörfl, Jörg‐Martin, Kühne, Ronald, Schmalz, Hans‐Günther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078984/
https://www.ncbi.nlm.nih.gov/pubmed/31961029
http://dx.doi.org/10.1002/chem.202000307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078984/
https://www.ncbi.nlm.nih.gov/pubmed/31961029
http://dx.doi.org/10.1002/chem.202000307

Ejemplares similares