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Cellulose ether treatment in vivo generates chronic wasting disease prions with reduced protease resistance and delayed disease progression

Chronic wasting disease (CWD) is a prion disease of free‐ranging and farmed cervids that is highly contagious because of extensive prion shedding and prion persistence in the environment. Previously, cellulose ether compounds (CEs) have been shown to significantly extend the survival of mice inocula...

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Detalles Bibliográficos
Autores principales: Hannaoui, Samia, Arifin, Maria Immaculata, Chang, Sheng Chun, Yu, Jie, Gopalakrishnan, Preetha, Doh‐ura, Katsumi, Schatzl, Hermann M., Gilch, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078990/
https://www.ncbi.nlm.nih.gov/pubmed/31553058
http://dx.doi.org/10.1111/jnc.14877