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Cellulose ether treatment in vivo generates chronic wasting disease prions with reduced protease resistance and delayed disease progression
Chronic wasting disease (CWD) is a prion disease of free‐ranging and farmed cervids that is highly contagious because of extensive prion shedding and prion persistence in the environment. Previously, cellulose ether compounds (CEs) have been shown to significantly extend the survival of mice inocula...
Autores principales: | Hannaoui, Samia, Arifin, Maria Immaculata, Chang, Sheng Chun, Yu, Jie, Gopalakrishnan, Preetha, Doh‐ura, Katsumi, Schatzl, Hermann M., Gilch, Sabine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078990/ https://www.ncbi.nlm.nih.gov/pubmed/31553058 http://dx.doi.org/10.1111/jnc.14877 |
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