Compactness of Protein Folds Alters Disulfide‐Bond Reducibility by Three Orders of Magnitude: A Comprehensive Kinetic Case Study on the Reduction of Differently Sized Tryptophan Cage Model Proteins

A new approach to monitor disulfide‐bond reduction in the vicinity of aromatic cluster(s) has been derived by using the near‐UV range (λ=266–293 nm) of electronic circular dichroism (ECD) spectra. By combining the results from NMR and ECD spectroscopy, the 3D fold characteristics and associated redu...

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Detalles Bibliográficos
Autores principales: Horváth, Dániel, Taricska, Nóra, Keszei, Ernő, Stráner, Pál, Farkas, Viktor, Tóth, Gábor K., Perczel, András
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079008/
https://www.ncbi.nlm.nih.gov/pubmed/31475422
http://dx.doi.org/10.1002/cbic.201900470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079008/
https://www.ncbi.nlm.nih.gov/pubmed/31475422
http://dx.doi.org/10.1002/cbic.201900470

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