Stereoselective Allylic Alkylations of Amino Ketones and Their Application in the Synthesis of Highly Functionalized Piperidines

Chelated ketone enolates are excellent nucleophiles for allylic alkylations. Electron‐withdrawing groups on the allyl moiety allow subsequent intramolecular Michael additions giving rise to piperidines with up to five stereogenic centers.[Image: see text]

Detalles Bibliográficos
Autores principales: Prudel, Cynthia, Huwig, Kai, Kazmaier, Uli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079034/
https://www.ncbi.nlm.nih.gov/pubmed/31943413
http://dx.doi.org/10.1002/chem.202000051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079034/
https://www.ncbi.nlm.nih.gov/pubmed/31943413
http://dx.doi.org/10.1002/chem.202000051

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