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Stereoselective Allylic Alkylations of Amino Ketones and Their Application in the Synthesis of Highly Functionalized Piperidines
Chelated ketone enolates are excellent nucleophiles for allylic alkylations. Electron‐withdrawing groups on the allyl moiety allow subsequent intramolecular Michael additions giving rise to piperidines with up to five stereogenic centers.[Image: see text]
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079034/ https://www.ncbi.nlm.nih.gov/pubmed/31943413 http://dx.doi.org/10.1002/chem.202000051 |