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LCMV‐specific CD4 T cell dependent polyclonal B‐cell activation upon persistent viral infection is short lived and extrafollicular

Persistent virus infections with non‐ or poorly cytopathic viruses are commonly associated with B cell dysregulations. These include the induction of hypergammaglobulinemia and the emergence of virus‐unspecific antibodies. These seemingly unspecific antibody responses interfere with the virus‐specif...

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Detalles Bibliográficos
Autores principales: Greczmiel, Ute, Kräutler, Nike J., Borsa, Mariana, Pedrioli, Alessandro, Bartsch, Ilka, Richter, Kirsten, Agnellini, Paola, Bedenikovic, Gregor, Oxenius, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079077/
https://www.ncbi.nlm.nih.gov/pubmed/31724162
http://dx.doi.org/10.1002/eji.201948286