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Crystal and solution structures of human oncoprotein Musashi‐2 N‐terminal RNA recognition motif 1

Musashi‐2 (MSI2) belongs to Musashi family of RNA binding proteins (RBP). Like Musashi‐1 (MSI1), it is overexpressed in a variety of cancers and is a promising therapeutic target. Both MSI proteins contain two N‐terminal RNA recognition motifs and play roles in posttranscriptional regulation of targ...

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Detalles Bibliográficos
Autores principales: Lan, Lan, Xing, Minli, Kashipathy, Maithri, Douglas, Justin, Gao, Philip, Battaile, Kevin, Hanzlik, Robert, Lovell, Scott, Xu, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079100/
https://www.ncbi.nlm.nih.gov/pubmed/31603583
http://dx.doi.org/10.1002/prot.25836