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Time‐to‐Event Modeling for Remimazolam for the Indication of Induction and Maintenance of General Anesthesia

Remimazolam is an ultra‐short‐acting benzodiazepine being investigated for induction and maintenance of general anesthesia and for procedural sedation. This dose‐response analysis of 4 phase 2‐3 studies evaluated covariates that may impact the pharmacodynamic profile (based on theoretical pharmacoki...

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Detalles Bibliográficos
Autores principales: Lohmer, Lauren L., Schippers, Frank, Petersen, Karl Uwe, Stoehr, Thomas, Schmith, Virginia D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079111/
https://www.ncbi.nlm.nih.gov/pubmed/31989598
http://dx.doi.org/10.1002/jcph.1552