DNA aptamers against the DUX4 protein reveal novel therapeutic implications for FSHD

Aberrant expression of the transcription factor double homeobox protein 4 (DUX4) can lead to a number of diseases including facio‐scapulo‐humeral muscular dystrophy (FSHD), acute lymphoblastic leukemia, and sarcomas. Inhibition of DUX4 may represent a therapeutic strategy for these diseases. By appl...

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Detalles Bibliográficos
Autores principales: Klingler, Christian, Ashley, Jon, Shi, Ke, Stiefvater, Adeline, Kyba, Michael, Sinnreich, Michael, Aihara, Hideki, Kinter, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079142/
https://www.ncbi.nlm.nih.gov/pubmed/32020675
http://dx.doi.org/10.1096/fj.201902696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079142/
https://www.ncbi.nlm.nih.gov/pubmed/32020675
http://dx.doi.org/10.1096/fj.201902696

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