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Whole‐genome analysis uncovers recurrent IKZF1 inactivation and aberrant cell adhesion in blastic plasmacytoid dendritic cell neoplasm

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and highly aggressive hematological malignancy with a poorly understood pathobiology and no effective therapeutic options. Despite a few recurrent genetic defects (eg, single nucleotide changes, indels, large chromosomal aberrations) hav...

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Detalles Bibliográficos
Autores principales: Bastidas Torres, Armando N., Cats, Davy, Mei, Hailiang, Fanoni, Daniele, Gliozzo, Jessica, Corti, Laura, Paulli, Marco, Vermeer, Maarten H., Willemze, Rein, Berti, Emilio, Tensen, Cornelis P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079160/
https://www.ncbi.nlm.nih.gov/pubmed/31846142
http://dx.doi.org/10.1002/gcc.22831