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Acid‐Cleavable Poly(ethylene glycol) Hydrogels Displaying Protein Release at pH 5

PEG is the gold standard polymer for pharmaceutical applications, however it lacks degradability. Degradation under physiologically relevant pH as present in endolysosomes, cancerous and inflammatory tissues is crucial for many areas. The authors present anionic ring‐opening copolymerization of ethy...

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Detalles Bibliográficos
Autores principales: Ewald, Johannes, Blankenburg, Jan, Worm, Matthias, Besch, Laura, Unger, Ronald E., Tremel, Wolfgang, Frey, Holger, Pohlit, Hannah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079179/
https://www.ncbi.nlm.nih.gov/pubmed/31850549
http://dx.doi.org/10.1002/chem.201905310