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Elevated Glutathione Peroxidase 2 Expression Promotes Cisplatin Resistance in Lung Adenocarcinoma

The aim of this study was to explore the roles of GPX2, a member of the glutathione peroxidase family (GPXs, GSH-Px), in cisplatin (DDP) resistance in lung adenocarcinoma (LUAD). GPX2 was found to be the most significantly upregulated gene in a DDP-resistant A549/DDP cell line compared with the pare...

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Detalles Bibliográficos
Autores principales: Du, He, Chen, Bi, Jiao, Nan-Lin, Liu, Yan-Hua, Sun, San-Yuan, Zhang, You-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079220/
https://www.ncbi.nlm.nih.gov/pubmed/32215178
http://dx.doi.org/10.1155/2020/7370157