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Cancer‐Cell‐Specific Drug Delivery by a Tumor‐Homing CPP‐Gossypol Conjugate Employing a Tracelessly Cleavable Linker

Tumor‐targeted drug delivery is highly important for improving chemotherapy, as it reduces the dose of cytotoxic agents and minimizes the death of healthy tissues. Towards this goal, a conjugate was synthesized of gossypol and a MCF‐7 cancer cell specific CPP (cell penetrating peptide), thus providi...

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Detalles Bibliográficos
Autores principales: Maity, Suman Kumar, Stahl, Paul, Hensel, Astrid, Knauer, Shirley, Hirschhäuser, Christoph, Schmuck, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079238/
https://www.ncbi.nlm.nih.gov/pubmed/31840306
http://dx.doi.org/10.1002/chem.201905159