Joint single cell DNA-seq and RNA-seq of gastric cancer cell lines reveals rules of in vitro evolution

Cancer cell lines are not homogeneous nor are they static in their genetic state and biological properties. Genetic, transcriptional and phenotypic diversity within cell lines contributes to the lack of experimental reproducibility frequently observed in tissue-culture-based studies. While cancer ce...

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Detalles Bibliográficos
Autores principales: Andor, Noemi, Lau, Billy T, Catalanotti, Claudia, Sathe, Anuja, Kubit, Matthew, Chen, Jiamin, Blaj, Cristina, Cherry, Athena, Bangs, Charles D, Grimes, Susan M, Suarez, Carlos J, Ji, Hanlee P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Standard Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079336/
https://www.ncbi.nlm.nih.gov/pubmed/32215369
http://dx.doi.org/10.1093/nargab/lqaa016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079336/
https://www.ncbi.nlm.nih.gov/pubmed/32215369
http://dx.doi.org/10.1093/nargab/lqaa016

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