The role of T cell trafficking in CTLA-4 blockade-induced gut immunopathology

BACKGROUND: Immune checkpoint inhibitor (ICPI) can augment the anti-tumour response by blocking negative immunoregulators with monoclonal antibodies. The anti-cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) antibody is the first ICPI which has shown remarkable benefits in the clinical treatment...

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Detalles Bibliográficos
Autores principales: Zhang, Shashuang, Liang, Wenhua, Luo, Lingjie, Sun, Shan, Wang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079427/
https://www.ncbi.nlm.nih.gov/pubmed/32183814
http://dx.doi.org/10.1186/s12915-020-00765-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079427/
https://www.ncbi.nlm.nih.gov/pubmed/32183814
http://dx.doi.org/10.1186/s12915-020-00765-9

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