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The role of T cell trafficking in CTLA-4 blockade-induced gut immunopathology

BACKGROUND: Immune checkpoint inhibitor (ICPI) can augment the anti-tumour response by blocking negative immunoregulators with monoclonal antibodies. The anti-cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) antibody is the first ICPI which has shown remarkable benefits in the clinical treatment...

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Detalles Bibliográficos
Autores principales:	Zhang, Shashuang, Liang, Wenhua, Luo, Lingjie, Sun, Shan, Wang, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079427/ https://www.ncbi.nlm.nih.gov/pubmed/32183814 http://dx.doi.org/10.1186/s12915-020-00765-9

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