Characterization of two in vivo challenge models to measure functional activity of monoclonal antibodies to Plasmodium falciparum circumsporozoite protein

BACKGROUND: New strategies are needed to reduce the incidence of malaria, and promising approaches include the development of vaccines and monoclonal antibodies (mAbs) that target the circumsporozoite protein (CSP). To select the best candidates and speed development, it is essential to standardize...

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Detalles Bibliográficos
Autores principales: Raghunandan, Rama, Mayer, Bryan T., Flores-Garcia, Yevel, Gerber, Monica W., Gottardo, Raphael, Jhun, Hugo, Herrera, Sonia M., Perez-Ramos, Daniel W., Locke, Emily, King, C. Richter, Zavala, Fidel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079517/
https://www.ncbi.nlm.nih.gov/pubmed/32183833
http://dx.doi.org/10.1186/s12936-020-03181-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079517/
https://www.ncbi.nlm.nih.gov/pubmed/32183833
http://dx.doi.org/10.1186/s12936-020-03181-0

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