Cargando…

Tumor necrosis factor α in aGVHD patients contributed to the impairment of recipient bone marrow MSC stemness and deficiency of their hematopoiesis-promotion capacity

BACKGROUND: Though accumulated evidence has demonstrated visceral organ involvement in acute graft-versus-host disease (aGVHD), how aGVHD influences the bone marrow (BM) niche and the reconstitution of hematopoiesis post-hematopoietic stem cell transplantation remains largely unknown. METHODS: In th...

Descripción completa

Detalles Bibliográficos
Autores principales: Ding, Li, Ning, Hong-Mei, Li, Pei-Lin, Yan, Hong-Min, Han, Dong-Mei, Zheng, Xiao-Li, Liu, Jing, Zhu, Ling, Xue, Mei, Mao, Ning, Guo, Zi-Kuan, Zhu, Heng, Wang, Heng-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079531/
https://www.ncbi.nlm.nih.gov/pubmed/32183881
http://dx.doi.org/10.1186/s13287-020-01615-9