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Identification, synthesis and evaluation of SARS-CoV and MERS-CoV 3C-like protease inhibitors

Severe acute respiratory syndrome (SARS) led to a life-threatening form of atypical pneumonia in late 2002. Following that, Middle East Respiratory Syndrome (MERS-CoV) has recently emerged, killing about 36% of patients infected globally, mainly in Saudi Arabia and South Korea. Based on a scaffold w...

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Detalles Bibliográficos
Autores principales: Kumar, Vathan, Tan, Kian-Pin, Wang, Ying-Ming, Lin, Sheng-Wei, Liang, Po-Huang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079562/
https://www.ncbi.nlm.nih.gov/pubmed/27240464
http://dx.doi.org/10.1016/j.bmc.2016.05.013