Inhibition of PI3Kδ Enhances Poly I:C-Induced Antiviral Responses and Inhibits Replication of Human Metapneumovirus in Murine Lungs and Human Bronchial Epithelial Cells

Viral infections of the airway can exacerbate respiratory diseases, such as asthma or chronic obstructive pulmonary disease (COPD), and accelerate disease progression. Phosphoinositide 3-kinase (PI3K)δ, a class 1A PI3K, has been studied as a potential target for achieving anti-oncogenic and anti-inf...

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Detalles Bibliográficos
Autores principales: Fujita, Akitaka, Kan-o, Keiko, Tonai, Ken, Yamamoto, Norio, Ogawa, Tomohiro, Fukuyama, Satoru, Nakanishi, Yoichi, Matsumoto, Koichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079687/
https://www.ncbi.nlm.nih.gov/pubmed/32218789
http://dx.doi.org/10.3389/fimmu.2020.00432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079687/
https://www.ncbi.nlm.nih.gov/pubmed/32218789
http://dx.doi.org/10.3389/fimmu.2020.00432

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