Cargando…

Mutations of the SL2 dimerization sequence of the hepatitis C genome abrogate viral replication

Stem-loop SL2 is a self-interacting palindromic sequence that has been identified within the hepatitis C virus genome (HCV). While, RNA dimerization of the HCV genome has been observed in vitro with short RNA sequences, the role of a putative RNA dimerization during viral replication has not been el...

Descripción completa

Detalles Bibliográficos
Autores principales: Masante, Cyril, Jaubert, Chloé, Palau, William, Plissonneau, Jacqueline, Besnard, Lucie, Ventura, Michel, Di Primo, Carmelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Basel 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079775/
https://www.ncbi.nlm.nih.gov/pubmed/25822205
http://dx.doi.org/10.1007/s00018-015-1893-3