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Mutations of the SL2 dimerization sequence of the hepatitis C genome abrogate viral replication
Stem-loop SL2 is a self-interacting palindromic sequence that has been identified within the hepatitis C virus genome (HCV). While, RNA dimerization of the HCV genome has been observed in vitro with short RNA sequences, the role of a putative RNA dimerization during viral replication has not been el...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Basel
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079775/ https://www.ncbi.nlm.nih.gov/pubmed/25822205 http://dx.doi.org/10.1007/s00018-015-1893-3 |