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Genetic studies of diseases: Predicting siRNA efficiency
Since the identification of RNA-mediated interference (RNAi) in 1998, RNAi has become an effective tool to inhibit gene expression. The inhibition mechanism is triggered by introducing a short interference double-stranded RNA (siRNA,19~27 bp) into the cytoplasm, where the guide strand of siRNA (usua...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Birkhäuser-Verlag
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079790/ https://www.ncbi.nlm.nih.gov/pubmed/17415516 http://dx.doi.org/10.1007/s00018-007-7057-3 |