Expression of Helicobacter pylori cag12 gene in Lactococcus lactis MG1363 and its oral administration to induce systemic anti-Cag12 immune response in mice

To develop an oral vaccine against Helicobacter pylori infection, we have expressed the H. pyloricag12 (HP0532) gene, encoding the outer membrane protein Cag12 (31 kDa), in a live delivery vehicle Lactococcus lactis. The cag12 gene was amplified by polymerase chain reaction (PCR) using the genomic D...

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Detalles Bibliográficos
Autores principales: Kim, Su-Jung, Jun, Do Youn, Yang, Chae Ha, Kim, Young Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2006
Materias:
Biotechnological Products and Process Engineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079898/
https://www.ncbi.nlm.nih.gov/pubmed/16586107
http://dx.doi.org/10.1007/s00253-005-0285-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079898/
https://www.ncbi.nlm.nih.gov/pubmed/16586107
http://dx.doi.org/10.1007/s00253-005-0285-2

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