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Inside-Out versus Outside-In models for virus induced demyelination: axonal damage triggering demyelination
The primary target in multiple sclerosis (MS) is believed to be either myelin itself (myelinopathy) or the myelin-forming cell, the oligodendrocyte (oligodendrogliopathy). Although axonal injury occurs in MS, it is regarded as a secondary event to the myelin damage. Here, the lesion develops from my...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2002
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079941/ https://www.ncbi.nlm.nih.gov/pubmed/12503060 http://dx.doi.org/10.1007/s00281-002-0105-z |