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Safety and immunogenicity of a potential checkpoint blockade vaccine for canine melanoma

Human immunotherapy with checkpoint blockades has achieved significant breakthroughs in recent years. In this study, a checkpoint blockade vaccine for canine melanoma was tested for safety and immunogenicity. Five healthy adult dogs received a mixture of three replication-defective chimpanzee-derive...

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Detalles Bibliográficos
Autores principales: Kurupati, Raj K., Zhou, Xiangyang, Xiang, Zhiquan, Keller, Lorraine H., Ertl, Hildegund C. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080056/
https://www.ncbi.nlm.nih.gov/pubmed/30051333
http://dx.doi.org/10.1007/s00262-018-2201-5