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High-level mucosal and systemic immune responses induced by oral administration with Lactobacillus-expressed porcine epidemic diarrhea virus (PEDV) S1 region combined with Lactobacillus-expressed N protein

To develop effective mucosal vaccine formulation against porcine epidemic diarrhea virus (PEDV) infection, the DNA fragments encoding spike protein immunodominant region S1 and nucleocapsid N of PEDV were inserted into pPG1 (surface-displayed) or pPG2 (secretory) plasmids followed by electrotransfor...

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Detalles Bibliográficos
Autores principales: Di-qiu, Liu, Jun-wei, Ge, Xin-yuan, Qiao, Yan-ping, Jiang, Song-mei, Liu, Yi-jing, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080084/
https://www.ncbi.nlm.nih.gov/pubmed/22134641
http://dx.doi.org/10.1007/s00253-011-3734-0