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Human CD27+ memory B cells colonize a superficial follicular zone in the palatine tonsils with similarities to the spleen. A multicolor immunofluorescence study of lymphoid tissue

BACKGROUND: Memory B cell (mBC) induction and maintenance is one of the keys to long-term protective humoral immunity. MBCs are fundamental to successful medical interventions such as vaccinations and therapy in autoimmunity. However, their lifestyle and anatomic residence remain enigmatic in humans...

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Detalles Bibliográficos
Autores principales: Lettau, Marie, Wiedemann, Annika, Schrezenmeier, Eva Vanessa, Giesecke-Thiel, Claudia, Dörner, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080255/
https://www.ncbi.nlm.nih.gov/pubmed/32187186
http://dx.doi.org/10.1371/journal.pone.0229778