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Human CD27+ memory B cells colonize a superficial follicular zone in the palatine tonsils with similarities to the spleen. A multicolor immunofluorescence study of lymphoid tissue
BACKGROUND: Memory B cell (mBC) induction and maintenance is one of the keys to long-term protective humoral immunity. MBCs are fundamental to successful medical interventions such as vaccinations and therapy in autoimmunity. However, their lifestyle and anatomic residence remain enigmatic in humans...
Autores principales: | Lettau, Marie, Wiedemann, Annika, Schrezenmeier, Eva Vanessa, Giesecke-Thiel, Claudia, Dörner, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080255/ https://www.ncbi.nlm.nih.gov/pubmed/32187186 http://dx.doi.org/10.1371/journal.pone.0229778 |
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