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P2Y6 receptor inhibition aggravates ischemic brain injury by reducing microglial phagocytosis

INTRODUCTION: Clearance of damaged cells and debris is beneficial for the functional recovery after ischemic brain injury. However, the specific phagocytic receptor that mediates microglial phagocytosis after ischemic stroke is unknown. AIM: To investigate whether P2Y6 receptor‐mediated microglial p...

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Detalles Bibliográficos
Autores principales: Wen, Ruo‐Xue, Shen, Hui, Huang, Shu‐Xian, Wang, Li‐Ping, Li, Zong‐Wei, Peng, Peng, Mamtilahun, Muyassar, Tang, Yao‐Hui, Shen, Fan‐Xia, Tian, Heng‐Li, Yang, Guo‐Yuan, Zhang, Zhi‐Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080436/
https://www.ncbi.nlm.nih.gov/pubmed/32154670
http://dx.doi.org/10.1111/cns.13296