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Recapitulating complex biological signaling environments using a multiplexed, DNA-patterning approach

Elucidating how the spatial organization of extrinsic signals modulates cell behavior and drives biological processes remains largely unexplored because of challenges in controlling spatial patterning of multiple microenvironmental cues in vitro. Here, we describe a high-throughput method that direc...

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Detalles Bibliográficos
Autores principales: Scheideler, Olivia J., Yang, Chun, Kozminsky, Molly, Mosher, Kira I., Falcón-Banchs, Roberto, Ciminelli, Emma C., Bremer, Andrew W., Chern, Sabrina A., Schaffer, David V., Sohn, Lydia L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080440/
https://www.ncbi.nlm.nih.gov/pubmed/32206713
http://dx.doi.org/10.1126/sciadv.aay5696