Development of a CRISPR-SaCas9 system for projection- and function-specific gene editing in the rat brain

A genome editing technique based on the clustered regularly interspaced short palindromic repeats (CRISPR)–associated endonuclease Cas9 enables efficient modification of genes in various cell types, including neurons. However, neuronal ensembles even in the same brain region are not anatomically or...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Haojie, Fu, Su, Cui, Shuang, Yin, Xiangsha, Sun, Xiaoyan, Qi, Xuetao, Cui, Kun, Wang, Jiaxin, Ma, Longyu, Liu, Feng-Yu, Liao, Fei-Fei, Wang, Xin-Hong, Yi, Ming, Wan, You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080442/
https://www.ncbi.nlm.nih.gov/pubmed/32206715
http://dx.doi.org/10.1126/sciadv.aay6687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080442/
https://www.ncbi.nlm.nih.gov/pubmed/32206715
http://dx.doi.org/10.1126/sciadv.aay6687

Ejemplares similares