CRISPR/Cas Systems in Genome Editing: Methodologies and Tools for sgRNA Design, Off‐Target Evaluation, and Strategies to Mitigate Off‐Target Effects

Life sciences have been revolutionized by genome editing (GE) tools, including zinc finger nucleases, transcription activator‐Like effector nucleases, and CRISPR (clustered regulatory interspaced short palindromic repeats)/Cas (CRISPR‐associated) systems, which make the targeted modification of geno...

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Detalles Bibliográficos
Autores principales: Manghwar, Hakim, Li, Bo, Ding, Xiao, Hussain, Amjad, Lindsey, Keith, Zhang, Xianlong, Jin, Shuangxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080517/
https://www.ncbi.nlm.nih.gov/pubmed/32195078
http://dx.doi.org/10.1002/advs.201902312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080517/
https://www.ncbi.nlm.nih.gov/pubmed/32195078
http://dx.doi.org/10.1002/advs.201902312

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