BRCA1 Deficiency Impairs Mitophagy and Promotes Inflammasome Activation and Mammary Tumor Metastasis

The breast cancer susceptibility gene 1 (BRCA1) is a major tumor suppressor gene and is most frequently mutated in hereditary breast cancer. BRCA1 plays a critical role in many biological processes, especially maintaining genomic stability in the nucleus, yet its role in the cytoplasm remains elusiv...

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Detalles Bibliográficos
Autores principales: Chen, Qiang, Lei, Josh Haipeng, Bao, Jiaolin, Wang, Haitao, Hao, Wenhui, Li, Licen, Peng, Cheng, Masuda, Takaaki, Miao, Kai, Xu, Jun, Xu, Xiaoling, Deng, Chu‐Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080549/
https://www.ncbi.nlm.nih.gov/pubmed/32195105
http://dx.doi.org/10.1002/advs.201903616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080549/
https://www.ncbi.nlm.nih.gov/pubmed/32195105
http://dx.doi.org/10.1002/advs.201903616

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