Proximity-induced caspase-9 activation on a DNA origami-based synthetic apoptosome

Living cells regulate key cellular processes by spatial organisation of catalytically active proteins in higher-order signalling complexes. These act as organising centres to facilitate proximity-induced activation and inhibition of multiple intrinsically weakly associating signalling components, wh...

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Detalles Bibliográficos
Autores principales: Rosier, Bas J.H.M., Markvoort, Albert J., Gumí Audenis, Berta, Roodhuizen, Job A.L., den Hamer, Anniek, Brunsveld, Luc, de Greef, Tom F.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080557/
https://www.ncbi.nlm.nih.gov/pubmed/32190819
http://dx.doi.org/10.1038/s41929-019-0403-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080557/
https://www.ncbi.nlm.nih.gov/pubmed/32190819
http://dx.doi.org/10.1038/s41929-019-0403-7

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