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Proximity-induced caspase-9 activation on a DNA origami-based synthetic apoptosome
Living cells regulate key cellular processes by spatial organisation of catalytically active proteins in higher-order signalling complexes. These act as organising centres to facilitate proximity-induced activation and inhibition of multiple intrinsically weakly associating signalling components, wh...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080557/ https://www.ncbi.nlm.nih.gov/pubmed/32190819 http://dx.doi.org/10.1038/s41929-019-0403-7 |