Cargando…

Efficacy and safety of PARP inhibitors as the maintenance therapy in ovarian cancer: a meta-analysis of nine randomized controlled trials

Purpose: Poly ADP ribose polymerase (PARP) inhibitors can effectively kill cancer cells by restraining the activity of DNA repair enzymes and utilizing the characteristics of BRCA mutations. This article evaluates the efficacy and safety of PARP inhibitors (PARPis) in the maintenance treatment of ov...

Descripción completa

Detalles Bibliográficos
Autores principales: Shao, Fengping, Liu, Jun, Duan, Yaoyun, Li, Li, Liu, Liqun, Zhang, Cai, He, Shanyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080644/
https://www.ncbi.nlm.nih.gov/pubmed/32096544
http://dx.doi.org/10.1042/BSR20192226