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Mechanisms of Anthracycline-Induced Cardiotoxicity: Is Mitochondrial Dysfunction the Answer?

Cardiac side effects are a major drawback of anticancer therapies, often requiring the use of low and less effective doses or even discontinuation of the drug. Among all the drugs known to cause severe cardiotoxicity are anthracyclines that, though being the oldest chemotherapeutic drugs, are still...

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Detalles Bibliográficos
Autores principales: Murabito, Alessandra, Hirsch, Emilio, Ghigo, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080657/
https://www.ncbi.nlm.nih.gov/pubmed/32226791
http://dx.doi.org/10.3389/fcvm.2020.00035