Combinatorial Treatment of Human Cardiac Engineered Tissues With Biomimetic Cues Induces Functional Maturation as Revealed by Optical Mapping of Action Potentials and Calcium Transients

Although biomimetic stimuli, such as microgroove-induced alignment (μ), triiodothyronine (T3) induction, and electrical conditioning (EC), have been reported to promote maturation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs), a systematic examination of their combinatorial effect...

Descripción completa

Detalles Bibliográficos
Autores principales: Wong, Andy On-Tik, Wong, Nicodemus, Geng, Lin, Chow, Maggie Zi-ying, Lee, Eugene K., Wu, Hongkai, Khine, Michelle, Kong, Chi-Wing, Costa, Kevin D., Keung, Wendy, Cheung, Yiu-Fai, Li, Ronald A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080659/
https://www.ncbi.nlm.nih.gov/pubmed/32226389
http://dx.doi.org/10.3389/fphys.2020.00165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080659/
https://www.ncbi.nlm.nih.gov/pubmed/32226389
http://dx.doi.org/10.3389/fphys.2020.00165

Ejemplares similares